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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
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Vertical Transmission of SARS-CoV-2: A Systematic Review
Ionara Diniz Evangelista Santos Barcelos1, Ivan Andrade de Araújo Penna2, Adriana de Góes Soligo3
1Department of Obstetrics and Gynecology, Universidade Estadual do Oeste do Paraná, Cascavel, Paraná, PR, Brazil.
Summary
The risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vertical transmission is very low. Only one confirmed case of SARS-CoV-2 vertical transmission was found among thousands of pregnant women. Further research is needed.
Area of Science:
- Virology
- Obstetrics and Gynecology
- Public Health
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause COVID-19, a global pandemic.
- Vertical transmission, from mother to child during pregnancy or childbirth, is a potential concern for infectious diseases.
Purpose of the Study:
- To evaluate the available evidence on the vertical transmission of SARS-CoV-2.
- To determine the risk of SARS-CoV-2 vertical transmission in pregnant women.
Main Methods:
- An extensive electronic literature search was conducted on Embase, PubMed, and Scopus databases.
- Records were screened for relevance, and full-text articles were reviewed to identify suspected cases of vertical transmission.
- Data extraction focused on delivery details, main findings, and conclusions of relevant systematic reviews.
Main Results:
- A total of 2,073 records were initially identified, with duplicates and ineligible studies excluded.
- Full-text review of 177 records revealed only 9 suspected cases of possible SARS-CoV-2 vertical transmission.
- One case, reported in France, presented sufficient evidence to confirm vertical transmission.
Conclusions:
- The risk of vertical transmission of SARS-CoV-2 appears to be very low.
- Despite a large number of infected pregnant women, confirmed cases of vertical transmission are rare.
- Further well-designed observational studies with large sample sizes are required to ascertain the precise risk and its relation to gestational age at infection.
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