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Does Delirium Phenomenology in Persons with Advanced Cancer Follow a Specific Pattern?
Maria Caterina Pallotti1,2, Jesus Lopez-Fidalgo3, Carlos Centeno3,4,5
1Seràgnoli Hospice Foundation, Bentivoglio, Italy.
Delirium phenomenology in advanced cancer patients often presents with cognitive symptoms like disorientation and memory issues. Early recognition of these patterns is key for timely diagnosis and improved patient care.
Area of Science:
- Oncology
- Geriatrics
- Psychiatry
Background:
- Delirium phenomenology (DP) recognition is crucial for early diagnosis and improved quality of life in advanced cancer patients.
- Understanding the neurobehavioral and cognitive patterns of delirium is essential for effective management.
Purpose of the Study:
- To identify the specific neurobehavioral and cognitive patterns associated with delirium in advanced cancer patients.
- To analyze the presentation and evolution of delirium phenomenology using a standardized assessment scale.
Main Methods:
- An observational, comparative, prospective study was conducted.
- The Memorial Delirium Assessment Scale (MDAS) was used to assess delirium phenomenology.
- 227 patients with advanced cancer were enrolled across different palliative care settings.
Main Results:
- Cognitive symptoms, including disorientation and memory impairment, were prevalent in patients with delirium.
- These cognitive deficits were also observed, though to a lesser extent, in patients without delirium, suggesting they may be early indicators.
- Delirium resolved in 22 patients, with significant improvement in MDAS scores (10.08 to 3.6, p < 0.001).
Conclusions:
- Cognitive-related symptoms are the most prevalent and appear to be the earliest signs of delirium phenomenology in advanced cancer patients.
- Early identification of these cognitive changes can aid in the timely diagnosis and management of delirium.
- Further research into the specific cognitive profiles of delirium in this population is warranted.
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