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Published on: August 7, 2017
The Infant Microbiome and Its Impact on Development of Food Allergy
Kylie N Jungles1, Kassidy M Jungles2, Leah Greenfield3
1Department of Pediatrics, University of Michigan C.S. Mott Children's Hospital, 1540 E Hospital Dr #4204, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Allergy and Immunology Division, Rush University Medical Center, 1725 West Harrison Street, Suite 117, Chicago, IL 60612, USA.
Abstract:
The prevalence of food allergy (FA) has been increasing over the past few decades; recent statistics suggest that FA has an impact on up to 10% of the population and 8% of children. Although the pathogenesis of FA is unclear, studies suggest gut microbiome plays a role in the development of FA. The gut microbiome is influenced by infant feeding method, infant diet, and maternal diet during lactation. Breastfeeding, Mediterranean diet, and probiotics are associated with commensal gut microbiota that protect against FA. This area of research is essential to discovering potential preventive methods or therapeutic targets against FA.
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