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Updated: Nov 9, 2025
External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
Efficacy of phloroglucinol for acceleration of labour: a systematic review and meta‑analysis
Fan Wu1, Yue Chen1, Caihong Zheng2
1Department of Pharmacy, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, 310006, China.
Purpose:
To assess the efficacy of phloroglucinol for acceleration of labour.
Methods:
Randomized controlled trials (RCTs) comparing phloroglucinol with placebo were searched in PubMed, Embase and the Cochrane Library. Literatures were collected up to April 2020. Primary outcomes were the duration of labour and average blood loss. Finally, a total of 4 RCTs, 377 patients were included in this meta-analysis. The included RCTs were analyzed by the software Rev Man 5. 3.
Results:
In the phloroglucinol group, the duration of the first stage was reduced by 116.04 min (95% CI 107.71 to 124.68), and the duration of the second stage was reduced by 10.75 min (95% CI 8.79 to 12.70). The average blood loss was reduced by 16.07 ml, which was statistically different from the control group.
Conclusion:
The application of phloroglucinol is proved to be effective for accelerating the labour process, reducing the risk of maternal and neonatal complications.
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