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Using compositional mixed-effects models to evaluate responses to amino acid supplementation in milk replacers for
M Terré1, I Ortuzar2, J Graffelman2
1Department of Ruminant Production, IRTA (Institut de Recerca i Tecnologia Agroalimentàries), 08140 Caldes de Montbui, Spain.
Journal of Dairy Science
|April 18, 2021
Summary
Supplementing milk replacers with specific amino acids (AA) like arginine, threonine, and lysine shows potential for improving calf growth and reducing serum urea. This study explored various AA combinations to optimize calf nutrition.
Area of Science:
- Animal Nutrition and Metabolism
- Ruminant Physiology
- Feed Science
Background:
- While lysine, methionine, and threonine supplementation in calf milk replacers is common, the impact of other amino acids (AA) remains less understood.
- Optimizing amino acid profiles in milk replacers is crucial for young calf growth and metabolic health.
- Limited research exists on the effects of non-essential and other essential amino acids beyond the standard supplementation.
Purpose of the Study:
- To evaluate the effects of four different amino acid combinations on the growth performance of Holstein male calves.
- To investigate the influence of amino acid supplementation on plasma amino acid concentrations and serum urea levels.
- To identify specific amino acid profiles that can optimize calf growth and metabolic efficiency.
Main Methods:
- Seventy-six Holstein male calves were fed one of four milk replacer formulations with varying amino acid supplements.
- Growth performance, feed intake, plasma amino acid concentrations, and serum urea were monitored throughout the study.
- Compositional data analysis and linear mixed-effects models were employed to analyze plasma amino acid data and its impact on growth and urea.
Main Results:
- No significant differences in overall calf performance or feed intake were observed among the treatment groups.
- Plasma concentrations of supplemented amino acids increased in respective treatment groups (KMT and PG).
- A specific combination of arginine, threonine, and lysine was identified as a key factor in reducing serum urea and enhancing growth.
Conclusions:
- Supplementation with arginine, threonine, and lysine, as a combined cluster, shows promise for optimizing calf growth.
- Further research into specific amino acid balances can lead to improved calf nutrition strategies.
- The study highlights the potential of targeted amino acid supplementation beyond standard formulations for calf development.
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