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Updated: Nov 8, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Challenges in the recognition and management of paediatric sepsis - The journey
Amanda Harley1, Luregn J Schlapbach2, Amy N B Johnston3
1School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, QLD, Australia; Child Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia; Department of Emergency Medicine, Gold Coast University Hospital, Gold Coast, QLD, Australia.
Insights
Paediatric sepsis is a major cause of childhood death and disability. A unified approach is needed, emphasizing families, pre-hospital care, and multidisciplinary post-sepsis support for better outcomes.
Area of Science:
- Pediatric critical care medicine
- Public health policy
- Emergency medicine
Background:
- Paediatric sepsis is a significant cause of mortality and long-term morbidity in children.
- Current guidelines focus on in-hospital management, with less emphasis on pre-hospital and post-sepsis care.
- A unified, holistic approach is essential for improving outcomes.
Purpose of the Study:
- To critically discuss challenges in paediatric sepsis care.
- To highlight the importance of family, pre-hospital, and multidisciplinary post-sepsis care.
- To inform future healthcare delivery and research in paediatric sepsis.
Main Methods:
- Literature review of contemporary research on paediatric sepsis.
- Critical discussion of key challenges in recognition and management.
- Analysis of the patient journey from pre-hospital to post-sepsis care.
Main Results:
- Paediatric sepsis requires a broader focus beyond hospital settings.
- The roles of families, paramedics, and nurses in early recognition are crucial but under-represented.
- Multidisciplinary, patient-centred care is vital for managing sequelae.
Conclusions:
- Enhanced recognition and management strategies for paediatric sepsis are needed.
- Integrating families and pre-hospital care into sepsis protocols is paramount.
- Further research into holistic, patient-centred paediatric sepsis care is essential.
Abstract:
Paediatric sepsis remains a leading cause of childhood death. Morbidity is high, with up to one third of children affected developing ongoing, sometimes lifelong sequelae. To address the major burden of sepsis on child health, there is need for a unified approach to care, as outlined in the Australian National Action Plan for sepsis. While the Surviving Sepsis Campaign 2020 guidelines provided evidence-based recommendations for sepsis management in hospital, additional emphasis on families, pre-hospital recognition and post-sepsis care incorporating the multidisciplinary team is paramount to achieve quality patient outcomes. The role of families, paramedics and nurses in recognising and managing paediatric sepsis remains an under-represented area in current literature. The aim of this paper is to critically discuss key challenges surrounding the journey of paediatric sepsis, drawing on contemporary literature to highlight key areas pertinent to recognition and management of sepsis in children. Application of a holistic, patient-centred focus will provide an overview of paediatric sepsis, aiming to inform future development for enhanced healthcare delivery and identify critical areas for further research.
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