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Updated: Nov 8, 2025

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Ginseng for erectile dysfunction.

Hye Won Lee1, Myeong Soo Lee2,3, Tae-Hun Kim4

  • 1Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea, South.

The Cochrane Database of Systematic Reviews
|April 19, 2021
PubMed
Summary
This summary is machine-generated.

Ginseng may offer a trivial benefit for erectile dysfunction (ED) and intercourse ability, but evidence is low certainty. This study found no significant improvements in erectile function or satisfaction compared to placebo.

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Area of Science:

  • Integrative medicine and sexual health research.
  • Clinical trial analysis of herbal supplements.

Background:

  • Ginseng is a popular herbal supplement used for various conditions, including erectile dysfunction (ED).
  • Existing studies on ginseng for ED are limited by small sample sizes and variable quality, yielding unclear results.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of ginseng for treating erectile dysfunction.

Main Methods:

  • A comprehensive systematic review and meta-analysis of randomized and quasi-randomized controlled trials.
  • Searches across multiple databases (CENTRAL, MEDLINE, Embase, etc.) up to January 2021.
  • Data extraction and risk of bias assessment by multiple authors, with evidence certainty rated using the GRADE approach.

Main Results:

  • Nine studies involving 587 men with mild to moderate ED were included, all comparing ginseng to placebo.
  • Ginseng showed a trivial effect on erectile function (IIEF-15 and IIEF-5 scores) and intercourse satisfaction, with low to moderate certainty evidence.
  • A potential improvement in self-reported ability to have intercourse was noted (low certainty evidence), with minimal impact on adverse events.

Conclusions:

  • Ginseng demonstrates likely trivial effects on erectile function and intercourse satisfaction compared to placebo, based on low certainty evidence.
  • While ginseng may enhance self-reported intercourse ability, its clinical significance for ED remains limited.
  • No evidence exists comparing ginseng to established ED treatments like phosphodiesterase-5 inhibitors.