[Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride]

Was to assess changes in the oral microbiota when using octenidine dihydrochloride mouthwash.

Quantitative and qualitative changes in the oral microbiota were studied and evaluated after a single rinse, course application and long-term dates.

A single rinse resulted in a significant decrease in the number of pathogenic microorganisms: S. aureus, C. albicans, and Enterobacteriae. After a seven-day course of mouthwash application, the complete disappearance of pathogenic microorganisms: S. aureus, S. albicans, and Enterobacteriae and an increase in the number of Lactobacillus spp were revealed. 7 days after the mouthwash was canceled, there was some recovery of pathogenic (S. aureus, Candida), the number of Lactobacillus spp. remained the same, normal microflora almost completely restored.

Octenidine dihydrochloride mouthwash may be recommended for wide use in dental practice in the treatment of various oral pathological conditions, including candidiasis and dysbiosis.