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Disease-Modifying Antirheumatic Drugs (DMARDs) and drug interactions in dentistry
C Muñoz-Martínez1, M Segura-Puertas, G Gómez-Moreno
1Department of Medically Compromised Patients in Dentistry, School of Dentistry, University of Granada, Granada, Spain. ggomez@ugr.es.
European Review for Medical and Pharmacological Sciences
|April 20, 2021
Summary
Disease-Modifying Antirheumatic Drugs (DMARDs) used for rheumatoid arthritis can interact with common dental medications. Dentists must be aware of these drug interactions to prevent adverse patient reactions.
Area of Science:
- Rheumatology
- Pharmacology
- Dental Medicine
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune condition requiring long-term management.
- Disease-Modifying Antirheumatic Drugs (DMARDs) are the primary treatment for RA, aiming to control disease activity.
- Dental procedures often necessitate the use of various medications, creating potential for drug interactions.
Purpose of the Study:
- To identify potential drug interactions between DMARDs and commonly prescribed dental medications.
- To prevent adverse drug reactions in patients with rheumatoid arthritis undergoing dental treatment.
Main Methods:
- A literature review was conducted using PubMed.
- Searches included terms related to rheumatoid arthritis, dentistry, drug interactions, and specific DMARDs (e.g., methotrexate, adalimumab).
Main Results:
- Most DMARDs exhibit potential interactions with a wide range of dental drugs.
- These interactions involve common dental medications such as antibiotics, analgesics, anesthetics, antifungals, and corticosteroids.
Conclusions:
- Oral health clinicians must be aware of potential drug interactions between DMARDs and dental drugs.
- Awareness is crucial for preventing adverse reactions and ensuring patient safety during dental care.
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