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Updated: Nov 8, 2025

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
Published on: October 2, 2016
[Multidisciplinary management of voluntary pink oleander poisoning: How to estimate the quantities ingested?]
C Combe1, J Guitton2, A Daudé3
1Service pharmacie, centre hospitalier de Valence, 179, boulevard Maréchal-Juin, 26000 Valence, France.
Abstract:
This is a case of voluntary ingestion of Nerium oleander leaves in an adolescent requiring the use of atropine and emergency chartering of antidigoxin antibodies (Digifab®) due to the difficulty of assessing oleandrin level and associated toxicity. Upon hospital admission, a digoxinemia was performed (0.44μg/mL) and the presence of oleandrine was detected. Oleandrin levels at toxic levels may be suspected by a measure of blood digoxin and explain the patient's clinical signs, which could adapt the therapeutic management.
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