Review Article--Clinical Overview of Myocardial Infarction Without Obstructive Coronary Artey Disease (MINOCA)
Fahad Shamsi1, Khwaja Y Hasan1, Shahrukh Hashmani1
1Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Journal of the Saudi Heart Association
|April 21, 2021
Summary
Myocardial infarction with non-obstructive coronary arteries (MINOCA) affects patients with heart attack symptoms but no blocked arteries. This review clarifies MINOCA
Area of Science:
- Cardiology
- Internal Medicine
- Pathophysiology
Background:
- Myocardial infarction with non-obstructive coronary arteries (MINOCA) is diagnosed when patients exhibit acute myocardial infarction (AMI) symptoms, but coronary angiography shows no significant blockages.
- MINOCA represents a heterogeneous group of conditions, leading to uncertainties regarding its prognosis, mortality predictors, and optimal management strategies.
Purpose of the Study:
- To provide a comprehensive overview of MINOCA.
- To elucidate the clinical features, diagnostic criteria, prevalence, and therapeutic approaches for MINOCA.
Main Methods:
- This is a review article.
- Literature search was conducted to gather information on MINOCA.
- Data on clinical presentation, diagnosis, treatment, and prognosis were synthesized.
Main Results:
- MINOCA encompasses diverse underlying causes.
- Standardized diagnostic criteria and treatment protocols for MINOCA are still evolving.
- Prognosis and mortality predictors in MINOCA patients require further investigation.
Conclusions:
- MINOCA is a complex clinical entity requiring further research.
- Understanding the heterogeneity of MINOCA is crucial for improving patient outcomes.
- Further studies are needed to establish optimal management guidelines and identify prognostic factors.


