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Surgical Labyrinthectomy of the Rat to Study the Vestibular System
Published on: May 19, 2018
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Pneumolabyrinth: a systematic review.
Cecilia Botti1, Andrea Castellucci2, Francesco Maria Crocetta2
1PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Via del Pozzo, 41125, Modena, Italy. botceci@gmail.com.
Summary
Pneumolabyrinth (PNL) often results from trauma or surgery, commonly affecting the vestibule. While vestibular symptoms usually resolve, hearing recovery after PNL is variable and less predictable.
Area of Science:
- Otolaryngology
- Neurosurgery
- Radiology
Background:
- Pneumolabyrinth (PNL) is a condition characterized by the presence of air within the labyrinthine structures of the inner ear.
- Understanding the causes, presentation, and outcomes of PNL is crucial for effective patient management.
Purpose of the Study:
- To systematically review the literature on the etiology, clinical and radiological presentation, surgical management, and outcomes of pneumolabyrinth (PNL).
Main Methods:
- A systematic literature review was conducted using major electronic databases up to September 2020.
- Studies were selected based on PRISMA standards, focusing on PNL etiology, clinical presentation, treatment, and outcomes.
- A qualitative synthesis of data from 78 included articles involving 132 patients was performed.
Main Results:
- The most frequent causes of PNL were temporal bone fracture (31.8%), stapes surgery (18.2%), penetrating trauma (15.9%), head trauma (14.4%), and barotrauma (11.4%).
- The vestibule was the most commonly affected site (95.3%), followed by the cochlea (40.2%) and semicircular canals (23.4%).
- Vestibular symptoms resolved in most patients, but hearing function prognosis was highly variable.
Conclusions:
- PNL can arise from traumatic, iatrogenic, or inflammatory/infective causes.
- Management options include surgical fistula sealing or conservative treatments.
- Current evidence is insufficient for definitive clinical decision-making due to low certainty.
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