Related Experiment Video

Updated: Nov 8, 2025

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
09:04

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy

Published on: February 20, 2018

12.7K

Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity

Rodrigo W Alves de Souza1, David Gallo2, Ghee Rye Lee2

  • 1Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA; School of Physical Education and Sport, University of São Paulo, São Paulo 05508030, Brazil.

Cell Reports
|April 21, 2021
PubMed

Keywords:
DAMPexercise traininghemeheme oxygenase-1hemopexinmitochondrial dysfunctionmuscle atrophymuscle microtraumasatellite cells

More Related Videos

Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases08:12

Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases

Published on: October 4, 2024

2.1K
Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice10:00

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

8.6K

Related Concept Videos

Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
4.6K
Classification of Skeletal Muscle Fibers01:48

Classification of Skeletal Muscle Fibers

Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
58.5K
Factors Affecting Respiration01:24

Factors Affecting Respiration

Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
8.2K
Energy Supply for Muscle Contraction01:25

Energy Supply for Muscle Contraction

Skeletal muscle fibers have the unique ability to switch between rest and contraction states, using different sources of ATP for energy. The contraction cycle and Ca2+ transport back into the sarcoplasmic reticulum for relaxation require significant ATP. However, the ATP reserves in muscle fibers are limited and can only sustain contractions for a few seconds. Additional ATP production becomes necessary for prolonged contractions. As a result, muscle fibers generate ATP through various sources,...
4.8K
Factors Affecting Erythropoiesis01:24

Factors Affecting Erythropoiesis

The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
4.4K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.3K