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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
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    Area of Science:

    • Medical Imaging
    • Biomedical Engineering
    • Machine Learning

    Background:

    • Ultrasound sound-speed tomography (USST) offers non-ionizing, cost-effective 3D breast imaging for cancer diagnosis.
    • Accurate first-arrival picking of transmission waves is critical for USST reconstruction quality.
    • Existing picking methods lack accuracy and robustness against noise.

    Purpose of the Study:

    • To develop an improved first-arrival picking method for USST.
    • To enhance the accuracy and robustness of wave picking using deep learning.
    • To improve the overall quality of USST breast imaging.

    Main Methods:

    • Introduction of a self-attention mechanism into a bidirectional long short-term memory (BLSTM) network, creating the SAT-BLSTM network.
    • The SAT-BLSTM network predicts the probability of first-arrival times, selecting the time with maximum probability.
    • Validation through numerical simulations and a prototype experiment.

    Main Results:

    • SAT-BLSTM achieved the lowest mean absolute errors (MAEs) in numerical simulations across various signal-to-noise ratios (SNRs): 48 ns (50 dB), 49 ns (30 dB), and 76 ns (15 dB).
    • In prototype experiments, SAT-BLSTM demonstrated superior performance with an MAE of 94 ns compared to BLSTM (111 ns) and AIC (410 ns).
    • The proposed method significantly outperformed traditional Akaike information criterion (AIC) and standard BLSTM methods.

    Conclusions:

    • The SAT-BLSTM network offers a significant advancement in first-arrival picking for USST.
    • This improved picking accuracy leads to enhanced USST image reconstruction and potentially more reliable breast cancer diagnosis.
    • The self-attention mechanism integration boosts robustness and accuracy in noisy environments.