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Lanthanide-based resonance energy transfer biosensors for live-cell applications

Ha Pham1, Lawrence W Miller1

  • 1Department of Chemistry, University of Illinois at Chicago, Chicago, IL, United States.

Methods in Enzymology
|April 23, 2021
PubMed
Summary

Lanthanide-based Förster resonance energy transfer (LRET) biosensors offer sensitive detection of protein-protein interactions (PPIs) in live cells. These biosensors enable advanced imaging and high-throughput screening for biological research.

Keywords:
BiosensorsHigh-throughput screeningLanthanidesLuminescenceMicroscopyProtein–protein interactions

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