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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

96
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Flail Chest-I01:24

Flail Chest-I

360
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
360
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Updated: Nov 8, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
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Clomiphene- induced pulmonary embolism.

Chahat Puri1, Eugene A Obah1

  • 1Internal Medicine Residency Program, Greater Baltimore Medical Center, Baltimore, MD, USA.

Journal of Community Hospital Internal Medicine Perspectives
|April 23, 2021
PubMed
Summary

Pulmonary embolism (PE) is a serious condition. A young male without risk factors developed PE after clomiphene therapy, highlighting a potential new risk factor.

Area of Science:

  • Cardiology
  • Pulmonology
  • Pharmacology

Background:

  • Pulmonary embolism (PE) and deep vein thrombosis (DVT) are significant causes of morbidity and mortality.
  • Established risk factors include smoking, immobilization, malignancy, trauma, oral contraceptive pills (OCPs), pregnancy, and surgery.
  • Diagnosis of PE often necessitates high clinical suspicion.

Observation:

  • A case report details a 31-year-old male patient with no prior risk factors for thromboembolism.
  • The patient developed a PE after a 5-month course of clomiphene therapy.

Findings:

  • Clomiphene therapy, commonly used for infertility, may be associated with an increased risk of PE in young males.
  • This case suggests clomiphene as a potential, previously unrecognized risk factor for PE.
Keywords:
Pulmonary embolismclomiphenedeep vein thrombosis

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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Implications:

  • Physicians should consider clomiphene therapy as a potential risk factor when evaluating young males presenting with PE.
  • Further research is warranted to elucidate the mechanism and confirm the association between clomiphene and thromboembolic events.
  • This finding may influence prescribing guidelines and patient counseling regarding clomiphene use.