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Related Experiment Videos

Pseudopapilledema associated with abnormally small optic discs.

J B Jonas1, G C Gusek, I Guggenmoos-Holzmann

  • 1Department of Ophthalmology, University Erlangen-Nürnberg, West-Berlin.

Acta Ophthalmologica
|April 1, 1988
PubMed
Summary
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Optic discs in patients with pseudopapilledema are significantly smaller than normal optic nerve heads. This reduced optic disc size may explain the condition

Area of Science:

  • Ophthalmology
  • Optic Nerve Health

Background:

  • Pseudopapilledema is a condition that mimics optic disc swelling.
  • The exact cause of pseudopapilledema is not fully understood.

Purpose of the Study:

  • To determine the absolute size of optic discs in individuals with pseudopapilledema.
  • To compare optic disc size in pseudopapilledema to normal optic nerve heads.

Main Methods:

  • Utilized Littmann's method for magnification correction in central fundus photographs.
  • Measured the optic disc area of 35 unselected patients with pseudopapilledema.
  • Performed statistical analysis (Student's t-test) to compare disc sizes.

Main Results:

  • Optic discs with pseudopapilledema had a significantly smaller mean area (1.95 mm²) compared to normal optic nerve heads (2.73 mm²).

Related Experiment Videos

  • No cupping was observed in the pseudopapilledema group.
  • High intraobserver (0.045) and interobserver (0.08) reliability was achieved.

    • Conclusions:

    • Markedly reduced optic disc size in pseudopapilledema may be linked to a small optic nerve scleral canal.
    • This size discrepancy could impede intraaxonal transport, leading to secondary optic nerve fiber swelling and disc prominence.
    • Pseudopapilledema may be associated with optic nerve head drusen, which also correlate with smaller optic discs.