Maxillary Anterior Teeth With Extensive Root Resorption Treated With Low-level Light-activated Engineered Chitosan...

Area of Science:

• Biomaterials Science
• Regenerative Dentistry
• Nanotechnology

Background:

• Photoactivated chitosan-based nanoparticles offer antimicrobial and regenerative properties.
• Inflammatory root resorption (IRR) with periapical lesions presents a significant clinical challenge.
• This study introduces rose bengal functionalized chitosan nanoparticles (CSRBnp) for treating extensive IRR.

Observation:

• A 17-year-old patient with extensive IRR in four maxillary teeth was treated with photoactivated CSRBnp.
• Treatment involved both intracanal and topical application of CSRBnp, along with Biodentine and bone grafting for defects.
• Follow-up at 26 months showed arrested IRR, no mobility, and significant osseous healing.

Findings:

• Photoactivated CSRBnp effectively halted IRR and promoted periradicular bone regeneration.
• The combined therapy resulted in complete healing of periapical lesions.
• The treatment demonstrated success even in a severe case with extensive root resorption.

Implications:

• Photoactivated chitosan nanoparticles represent a promising therapeutic strategy for managing severe IRR.
• This approach can significantly improve healing outcomes in complex endodontic cases.
• Further research into CSRBnp could lead to advanced regenerative treatments in dentistry.