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Optimizing Implementation in Cancer Control (OPTICC): protocol for an implementation science center.

Cara C Lewis1, Peggy A Hannon2, Predrag Klasnja3,4

  • 1Kaiser Permanente Washington Health Research Institute, 1730 Minor Avenue, Suite 1600, Seattle, WA, 98101, USA. cara.c.lewis@kp.org.

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Summary
This summary is machine-generated.

Optimizing Implementation in Cancer Control (OPTICC) will develop and test efficient methods to improve the use of evidence-based interventions (EBIs) in cancer care. This initiative aims to build capacity in implementation science for better cancer outcomes.

Keywords:
Agile scienceCancer controlCancer preventionCancer screeningDeterminantsImplementation scienceMechanismsOptimizationStrategies

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Area of Science:

  • Implementation Science
  • Cancer Control
  • Health Services Research

Background:

  • Evidence-based interventions (EBIs) have the potential to significantly reduce cancer mortality but are often implemented suboptimally.
  • The Optimizing Implementation in Cancer Control (OPTICC) center is established to address this gap within the National Cancer Institute Implementation Science Consortium.
  • Suboptimal implementation hinders the full impact of EBIs, leading to preventable cancer deaths.

Purpose of the Study:

  • To develop, test, and refine innovative and efficient methods for optimizing the implementation of EBIs in cancer control.
  • To establish a diverse implementation laboratory (I-Lab) for rapid implementation studies across the cancer care continuum.
  • To build capacity in implementation science through training and engagement of researchers.

Main Methods:

  • The OPTICC center is structured around three cores: Administrative, Implementation Laboratory (I-Lab), and Research Program.
  • A three-stage approach is employed: (I) identify and prioritize determinants, (II) match strategies, and (III) optimize strategies.
  • Methods leverage multiphase optimization strategies, user-centered design, and agile science principles.

Main Results:

  • The OPTICC center will generate and refine efficient and economical methods for EBI implementation.
  • The I-Lab will facilitate diverse clinical and community-based implementation studies.
  • Capacity building will train new investigators and engage existing ones in cancer-focused implementation science.

Conclusions:

  • OPTICC will advance the science of implementation to improve cancer control.
  • Dissemination of refined methods will occur through toolkits, online courses, and an interactive website.
  • The center aims to build a robust implementation science infrastructure for cancer control research.