Complex Regional Pain Syndrome and Distal Radius Fracture: Etiology, Diagnosis, and Treatment

Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by a constellation of signs and symptoms including pain out of proportion to the injury or insult, autonomic dysfunction, trophic changes, and impaired function. CRPS may occur following either conservative or surgical management of distal radius fractures and can significantly complicate the trajectory of a patient's recovery. Although the incidence, diagnosis, prevention, and treatment of this condition have been extensively studied, optimal methods to identify, prevent, and treat this condition remain controversial. This article reviews the available literature on the diagnosis and treatment of CRPS in distal radius fractures.