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Updated: Nov 8, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Primary Malignant Melanoma of the Urinary Bladder
Elizabeth Snajdar1, Andrina R Ajo2, Katie Rosen1
1Department of Urology, McLaren Macomb Hospital, Macomb, USA.
Primary malignant melanoma of the bladder is rare, with only 30 cases documented. This rare bladder cancer has a poor prognosis, as exemplified by a patient who died 16 months after diagnosis.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Primary malignant melanoma of the bladder is an exceptionally rare tumor.
- Fewer than 30 cases have been reported in medical literature.
- The prognosis for this condition is generally poor.
Observation:
- A 78-year-old female presented with new-onset urinary incontinence and intermittent hematuria.
- No evidence of primary melanoma was found elsewhere in the body.
- The patient had a rare primary malignant melanoma of the bladder.
Findings:
- The patient underwent cystectomy and ileal conduit surgery.
- Adjuvant chemotherapy was planned.
- Despite treatment, the patient died within 16 months due to metastatic disease.
Implications:
- This case highlights the aggressive nature and poor prognosis of primary bladder melanoma.
- Further research into effective treatments for this rare malignancy is warranted.
- Early diagnosis and management strategies are crucial for improving patient outcomes.
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