Related Experiment Video
Updated: Nov 8, 2025

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
Published on: February 27, 2015
Non-destructive State Detection and Spectroscopy of Single Molecules
Mudit Sinhal1, Ziv Meir1, Stefan Willitsch2
1Department of Chemistry, University of Basel, Klingelbergstrasse 80, CH-4056 Basel, Switzerland.
We developed a non-destructive quantum-state detection method for single trapped molecules using an atomic ion probe. This technique enables precise molecular spectroscopy and opens new avenues for fundamental physics research.
Area of Science:
- Quantum physics
- Molecular spectroscopy
- Atomic physics
Background:
- Quantum-state detection of molecules is challenging due to their fragility.
- Precise control over molecular quantum states is crucial for advanced applications.
Purpose of the Study:
- To present a novel method for non-destructive quantum-state detection and spectroscopy of single trapped molecules.
- To explore new research directions in precision spectroscopy and fundamental physics.
Main Methods:
- Utilizing a single atomic ion as a probe for a single molecular ion.
- Implementing a scheme that avoids destruction or perturbation of the molecule's quantum state.
Main Results:
- Demonstrated successful non-destructive quantum-state detection of single trapped molecules.
- Achieved probing of molecular states without altering them.
Conclusions:
- The developed method offers new perspectives for precision spectroscopy.
- Enables the development of new frequency standards and tests of fundamental physical concepts.
- Facilitates precise studies of chemical reactions and collisions with full quantum-state control.
Related Concept Videos
Molecular Spectroscopy: Absorption and Emission
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
¹³C NMR: ¹H–¹³C Decoupling
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
Atomic Spectroscopy: Absorption, Emission, and Fluorescence
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
High-Performance Liquid Chromatography: Types of Detectors

