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Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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Educational attainment does not influence brain aging.

Lars Nyberg1,2,3,4, Fredrik Magnussen4, Anders Lundquist3

  • 1Department of Radiation Sciences, Radiology, Umeå University, 901 87 Umeå, Sweden; lars.nyberg@umu.se a.m.fjell@psykologi.uio.no.

Proceedings of the National Academy of Sciences of the United States of America
|April 27, 2021
PubMed
Summary
This summary is machine-generated.

Higher education does not slow brain aging. This study found no evidence that years of education impact the rate of brain atrophy in the cortex and hippocampus over time.

Keywords:
agingcerebral cortexeducationhippocampusreserve

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Area of Science:

  • Neuroscience
  • Cognitive Aging
  • Educational Neuroscience

Background:

  • Education is linked to positive life outcomes.
  • The hypothesis that education slows brain aging is influential.
  • Understanding factors influencing brain aging is crucial.

Purpose of the Study:

  • To investigate the relationship between higher education and the rate of brain aging.
  • To determine if education influences longitudinal changes in brain structure.

Main Methods:

  • Longitudinal structural magnetic resonance imaging (MRI) data from 4,422 observations were analyzed.
  • Cross-sectional associations between education and regional cortical volume were examined.
  • Rates of change in brain structure (cortex and hippocampus) were assessed in relation to education.

Main Results:

  • Education showed a modest cross-sectional association with regional cortical volume.
  • Despite significant brain atrophy, education did not affect the rate of cortical or hippocampal aging.
  • Findings were consistent across two independent samples.

Conclusions:

  • The study challenges the prevailing view that higher education decelerates brain aging.
  • Education's impact on the rate of brain aging may be less significant than previously hypothesized.
  • Further research is needed to explore the complex relationship between education and brain health over the lifespan.