Related Experiment Video
Updated: Aug 15, 2026

Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging
Published on: January 27, 2015
[Research progress of the relationship between Candida albicans and dental caries]
1Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Experimental Teaching Demonstration Center, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Abstract:
Candida albicans (Ca) is an important opportunistic pathogenic fungus found in the oral cavity, which plays an important role in oral microecological balance, and often interacting with other bacteria including Streptococcus mutans (Sm). Meanwhile, the characteristics of Ca such as adhesion, acidogenicity, aciduric nature and the ability to produce collagenolytic proteinases indicate its latent cariogenic potential. This review summarizes the research progress of the detectable rate of Ca in caries, its cariogenic potential and the interaction with Sm and other oral bacteria, in order to extend the understanding of pathogenesis of dental caries and to contribute new therapeutic and preventive strategies for dental caries.
Related Concept Videos
The Oral Microbiota
Development of the Oral Microbiota
Candidiasis

