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Updated: Nov 7, 2025

Electron Cryotomography of Bacterial Cells
Published on: May 6, 2010
[Cryo-electron microcopy for a new vision of the cell and its components]
Daniel Lévy1, Aurélie Di Cicco1, Aurélie Bertin1
1Institut Curie, Université PSL, Sorbonne Université, CNRS UMR 168, Laboratoire Physico- Chimie Curie, 11 rue Pierre et Marie Curie, 75005 Paris, France.
Abstract:
Cryo-electron microscopy (cryo-EM) is a technique for imaging biological samples that plays a central role in structural biology, with high impact on research fields such as cell and developmental biology, bioinformatics, cell physics and applied mathematics. It allows the determination of structures of purified proteins within cells. This review describes the main recent advances in cryo-EM, illustrated by examples of proteins of biomedical interest, and the avenues for future development.
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