Related Experiment Video

Updated: Nov 7, 2025

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

1.0K

Pharmaceutical care program for ischemic stroke patients: a randomized controlled trial

Jianxin Wang1, Jing Wang1, Shuocheng Qiu2

  • 1Department of Pharmacy, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.

International Journal of Clinical Pharmacy
|April 28, 2021
PubMed

Insights

A pharmaceutical care program significantly improved medication adherence and risk factor control in ischemic stroke patients, leading to fewer hospital readmissions. This approach is key for effective secondary stroke prevention.

Area of Science:

  • Clinical Pharmacy
  • Neurology
  • Cardiovascular Medicine

Background:

  • Effective secondary prevention strategies are crucial for reducing stroke recurrence.
  • Post-stroke care requires comprehensive management of risk factors like blood pressure, blood glucose, and lipid profiles.

Purpose of the Study:

  • To evaluate the impact of a pharmaceutical care program on risk factor control in post-stroke patients.
  • To assess the effect of pharmaceutical care on medication adherence and hospital readmissions after ischemic stroke.

Main Methods:

  • A parallel randomized-controlled study involving ischemic stroke patients.
  • Patients were assigned to either a control group (no pharmaceutical care) or an intervention group receiving monthly pharmaceutical care for 6 months.
  • Interventions included education and counseling to enhance medication adherence and risk factor management; outcomes measured included blood pressure, blood glucose, lipid profile, and medication adherence.

Main Results:

  • The intervention group showed significantly higher medication adherence rates for antihypertensive, anti-diabetic, and lipid-lowering drugs compared to the control group.
  • More patients in the intervention group achieved target levels for hemoglobin A1c and low-density lipoprotein-cholesterol.
  • Hospital readmission rates were significantly lower in the intervention group (7.14%) compared to the control group (18.3%).

Conclusions:

  • Pharmaceutical care programs are effective in improving risk factor control for secondary stroke prevention.
  • These programs enhance medication adherence and reduce hospital readmissions in patients following an ischemic stroke.

Keywords:
ChinaIschemic strokePharmacistsSecondary prevention

More Related Videos

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.3K
Prehospital Thrombolysis: A Manual from Berlin05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.1K

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
93
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
73
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
95
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
305
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
91
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.2K