Morphological criteria for prognosis of endometrial carcinoma with special regard to nuclear grading

Histological and cytological prognostic factors have nowadays become indispensible criteria in planning the individualized surgical therapy of endometrial carcinoma. These factors can already be determined preoperatively on the basis of the fractionated curettage specimen with great reliability. A correction might be necessary after surgery in order to induce an individual postoperative therapy, if required, or to do without further treatment with benefit for the patient. In our investigations, nuclear grading has proved to be the most reliable prognostic factor.