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Clinical importance of nuclear progesterone receptor (PR) in endometrial adenocarcinoma

S Rakar1, S Rainer, H Lenasi

  • 1Department of Gynecology and Obstetrics, University of Ljubljana, Yugoslavia.

European Journal of Gynaecological Oncology
|January 1, 1988
PubMed

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Nuclear receptors, or NRs, are unique transcription factors that regulate gene transcription and affect the cellular pathways involved in reproduction, development, or metabolism. Their ability to be stimulated by small lipophilic ligands and control vital cellular processes makes them ideal drug targets. Nearly 10-15% of currently prescribed drugs target these receptors.
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