Comparison between Widefield Optical Coherence Tomography Devices in Eyes with High Myopia

Area of Science:

• Ophthalmology
• Medical Imaging
• Retinal Imaging

Background:

• High myopia presents challenges for visualizing retinal and subretinal layers.
• Optical coherence tomography (OCT) is crucial for assessing ocular structures.

Purpose of the Study:

• To compare the performance of four OCT devices in imaging highly myopic eyes.
• To evaluate differences in retinal visualization, artifact prevalence, and retrobulbar tissue imaging.

Main Methods:

• Prospective, observational, cross-sectional study involving patients with high myopia and controls.
• Four OCT devices (Spectralis OCT2, PlexElite 2.0 100 kHz, PlexElite 2.0 200 kHz, Canon Xephilio OCT-S1) were used.
• Standardized line scans centered on the fovea were acquired for comparison.

Main Results:

• Canon Xephilio OCT-S1 visualized the largest retinal extent (p < 0.0001).
• Spectralis OCT showed a higher prevalence of conjugate image artifacts (p < 0.0001), while PlexElite 200 kHz showed a lower prevalence (p < 0.0001).
• Swept-source PlexElite devices visualized retrobulbar tissue in a higher proportion of eyes (p < 0.007).

Conclusions:

• OCT device choice impacts the visualization of retinal structures and retrobulbar tissue in high myopia.
• Significant differences exist in artifact prevalence and imaging extent among the tested OCT devices.
• These findings aid in selecting appropriate OCT technology for high myopia research and clinical practice.