Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target

Area of Science:

• Nuclear Physics
• Medical Physics
• Accelerator Technology

Background:

• Boron Neutron Capture Therapy (BNCT) requires a reliable neutron source.
• Existing neutron sources may have limitations in energy, stability, or portability.
• Compact accelerator-based neutron sources offer a promising alternative.

Purpose of the Study:

• To design and construct a compact accelerator-based neutron source for BNCT.
• To characterize the neutron beam properties for therapeutic applications.
• To facilitate in vitro and in vivo research and clinical trials for BNCT.

Main Methods:

• Utilizing an original design tandem accelerator to generate a proton beam (0.6-2.3 MeV).
• Employing the ⁷Li(p,n)⁷Be threshold reaction for neutron flux generation.
• Implementing a beam-shaping assembly to produce epithermal neutrons suitable for BNCT.

Main Results:

• Achieved high proton beam energy stability (0.1%) and adjustable current (0.3-10 mA) with 0.4% stability.
• Successfully generated epithermal neutron beams with characteristics optimized for BNCT.
• Conducted research on blistering effects on neutron yield and developed dosimetry methods.

Conclusions:

• The developed compact accelerator-based neutron source is suitable for BNCT research and applications.
• The facility is progressing towards certification and clinical trials.
• The design serves as a successful prototype for clinical facilities.