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Related Experiment Video

Updated: Nov 7, 2025

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment

Published on: March 2, 2016

Special Issue "Arenaviruses 2020".

Igor S Lukashevich^1,2, Juan Carlos de la Torre³

¹Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, KY 40202, USA.

|April 30, 2021

Summary

Rodent-borne arenaviruses are typically linked to specific African muroid rodents or New World Cricetidae species. This study explores the broader host range and evolutionary history of these significant viral pathogens.

Area of Science:

Virology
Zoonotic Diseases
Evolutionary Biology

Background:

Keywords:

Lassa fever Lassa virus (LASV)lymphocytic choriomeningitis virus (LCMV)molecular virology of mammalian arenaviruses vaccine development

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Last Updated: Nov 7, 2025

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Rodent-borne arenaviruses are a significant group of zoonotic viruses.

Traditionally, African and New World arenaviruses are associated with distinct rodent host families (Mastomys/Praomys and Cricetidae, respectively).

Understanding the host-pathogen relationship is crucial for predicting and preventing spillover events.