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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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lncRNA - Long Non-coding RNAs02:39

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Types of RNA01:20

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Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
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Types of RNA01:23

Types of RNA

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Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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RNA Interference01:23

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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siRNA - Small Interfering RNAs02:30

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Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
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Long Non-Coding RNAs in Insects.

Chhavi Choudhary1, Shivasmi Sharma2, Keshav Kumar Meghwanshi1

  • 1Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandarsindari, Ajmer 305801, India.

Animals : an Open Access Journal From MDPI
|April 30, 2021
PubMed
Summary
This summary is machine-generated.

Regulatory non-coding RNAs (ncRNAs), particularly long non-coding RNAs (lncRNAs), play crucial roles in insect biology. This review details the functions and mechanisms of insect lncRNAs, highlighting their importance beyond protein-coding genes.

Keywords:
LncRNAsdevelopmentinsectsnon-coding RNAregulatory functions

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Area of Science:

  • Molecular Biology
  • Genomics
  • Entomology

Background:

  • Most transcribed RNAs are non-coding, serving regulatory functions as non-coding RNAs (ncRNAs).
  • ncRNAs encompass small non-coding RNAs (sncRNAs) and long non-coding RNAs (lncRNAs), with lncRNAs gaining significant attention for their regulatory roles.
  • Insects, a highly abundant and diverse animal group, exhibit lncRNA involvement in development, reproduction, and genetic plasticity.

Purpose of the Study:

  • To review the functions of insect long non-coding RNAs (lncRNAs).
  • To elucidate the molecular mechanisms underlying the action of various discovered insect lncRNAs.
  • To consolidate current knowledge on the significance of lncRNAs in insect biology.

Main Methods:

  • Literature review of recent studies on insect lncRNAs.
  • Analysis of reported functions and molecular mechanisms of lncRNAs in insects.
  • Synthesis of findings to provide a comprehensive overview.

Main Results:

  • lncRNAs are implicated in nearly all facets of insect life, including development and reproduction.
  • Diverse molecular mechanisms are employed by lncRNAs to regulate gene expression and biological processes.
  • lncRNAs are critical regulators in insects, challenging the notion of them being 'junk' transcripts.

Conclusions:

  • Insect lncRNAs are vital regulatory molecules with diverse functions.
  • Understanding lncRNA mechanisms is key to comprehending insect biology and evolution.
  • Further research into insect lncRNAs promises insights into development, plasticity, and potential applications.