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Updated: Nov 7, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Differences in Health-Related Quality of Life After Gastric Bypass Surgery: a Cross-Sectional Study
Tobias Antonsson1, André Wennersten2,3, Kaisa Sörensen4
1Department of Clinical Sciences Malmö, Section for Surgery, Skåne University Hospital, Lund University, Lund, Sweden. tobias.antonsson@med.lu.se.
Background:
Gastric bypass (GBP) is a surgical method with good evidence of sustainable weight loss, reduced obesity-related comorbidities, and improved health-related quality of life (HRQoL). However, long-term data post-GBP is scarce on HRQoL related to other factors than weight loss, such as impact of socio-economic, age, and gender.
Aim:
To investigate long-term HRQoL in GBP patients.
Methods:
The study was conducted as a cross-sectional study covering 3 to 9 years post-GBP measuring HRQoL using RAND-36. Association to weight loss, time since surgery, gender, educational level, occupation, and age was analyzed. The participants were included on the basis that they had received a GBP that was performed by Region Skåne, the southernmost administrative healthcare region in Sweden. Recruitment to the study was by mail invitation for an online survey.
Results:
Of the total population of 5310 persons receiving the questionnaire, 1339 of the 1372 responders fulfilled the inclusion criteria. Those with low educational level, unemployed, persons on sick leave or disability support, and those with less weight loss reported the lowest HRQoL. The longer time since surgery, the lower the HRQoL.
Conclusion:
Less weight loss, longer time since GBP, lower educational level, and lower degree of employment all affect HRQoL negatively after GBP surgery.
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