Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

130
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
130
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

164
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
164
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

141
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
141
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

113
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
113
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

82
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
82
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

153
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
153

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Restrictive filling pattern of transmitral inflow in acute decompensated heart failure with preserved ejection fraction: insights from the KCHF registry.

Open heart·2026
Same author

Association of Geographical Distance and Residential Population Density With Clinical Outcomes in Acute Decompensated Heart Failure: Insights From the Kyoto Congestive Heart Failure (KCHF) Registry.

Circulation reports·2026
Same author

Correction to: Standardization of Baseline and Provocative Invasive Hemodynamic Protocols for the Evaluation of Heart Failure and Pulmonary Hypertension: A Scientific Statement From the American Heart Association.

Circulation. Heart failure·2026
Same author

Utility of patient-reported perception of symptom change in patients with acute decompensated heart failure in predicting post-discharge clinical outcomes: insights from KCHF registry.

European heart journal. Quality of care & clinical outcomes·2026
Same author

Prevalence and clinical significance of guideline-directed medical therapy in acute heart failure with reduced or mildly reduced ejection fraction.

Scientific reports·2026
Same author

Standardization of Baseline and Provocative Invasive Hemodynamic Protocols for the Evaluation of Heart Failure and Pulmonary Hypertension: A Scientific Statement From the American Heart Association.

Circulation. Heart failure·2026

Related Experiment Video

Updated: Nov 7, 2025

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

839

A decrease in tricuspid regurgitation pressure gradient associates with favorable outcome in patients with heart

Yuta Seko1, Takao Kato1, Takeshi Morimoto2

  • 1Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

ESC Heart Failure
|May 2, 2021
PubMed
Summary

A decrease in tricuspid regurgitation pressure gradient (TRPG) after acute decompensated heart failure (ADHF) hospitalization is linked to better outcomes. Patients showing a TRPG drop had a lower risk of death and rehospitalization within six months.

Keywords:
Heart failureHospitalizationMortalityProspectiveTricuspid regurgitation pressure gradient

More Related Videos

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

1.2K
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.7K

Related Experiment Videos

Last Updated: Nov 7, 2025

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

839
Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

1.2K
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.7K

Area of Science:

  • Cardiology
  • Heart Failure Research
  • Echocardiography

Background:

  • Tricuspid regurgitation pressure gradient (TRPG) is a known prognostic marker in heart failure (HF).
  • The clinical significance of a decreasing TRPG during follow-up in acute decompensated heart failure (ADHF) remains understudied.

Purpose of the Study:

  • To investigate the association between a decrease in TRPG from hospitalization to a 6-month follow-up visit and subsequent clinical outcomes in ADHF patients.

Main Methods:

  • A cohort of 721 patients with ADHF and available TRPG data at hospitalization and 6 months was analyzed.
  • Patients were categorized into two groups: those with a TRPG decrease (>10 mmHg) and those without.
  • The primary outcome was a composite of all-cause death or HF hospitalization within 6 months.

Main Results:

  • The group with a TRPG decrease (N=179) showed a significantly lower 6-month cumulative incidence of the primary outcome compared to the no-decrease group (N=542) (12.2% vs. 18.7%, P=0.02).
  • Adjusted analysis revealed a significantly lower risk of the primary outcome in the TRPG decrease group (HR: 0.56, 95% CI: 0.32-0.93, P=0.02).
  • This reduced risk was consistent across different baseline TRPG values.

Conclusions:

  • A decrease in TRPG at 6 months post-discharge for ADHF is associated with a reduced risk of subsequent all-cause death and HF hospitalization.
  • This finding holds true regardless of the initial TRPG levels, suggesting a favorable prognostic implication of TRPG reduction.