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Brain connectivity alterations after additional sensorimotor or motor therapy for the upper limb in the early-phase
Nele De Bruyn1, Leen Saenen1, Liselot Thijs1
1Department of Rehabilitation Sciences, KU Leuven-University of Leuven, 3001 Leuven, Belgium.
Abstract:
Somatosensory function plays an important role for upper limb motor learning. However, knowledge about underlying mechanisms of sensorimotor therapy is lacking. We aim to investigate differences in therapy-induced resting-state functional connectivity changes between additional sensorimotor compared with motor therapy in the early-phase post stroke. Thirty first-stroke patients with a sensorimotor impairment were included for an assessor-blinded multi-centre randomized controlled trial within 8 weeks post stroke [13 (43%) females; mean age: 67 ± 13 years; mean time post stroke: 43 ± 13 days]. Patients were randomly assigned to additional sensorimotor (
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