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Chronic Constipation: Gastroenterohepatologist's Approach
Tomica Milosavljevic1, Dusan D Popovic2,3, Dragana Danilo Mijac2,3
1General Hospital "Euromedik,", Belgrade, Serbia.
Constipation affects 16% of people and requires a thorough evaluation. Treatment starts with lifestyle changes, progressing to medications or surgery for severe cases.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Constipation is a prevalent gastrointestinal disorder, affecting approximately 16% of the population.
- It can be classified as either primary or secondary in nature.
Purpose of the Study:
- To outline the diagnostic and therapeutic strategies for managing constipation.
- To emphasize the importance of a systematic approach in clinical practice.
Main Methods:
- Initial assessment involves a detailed medical history and physical examination.
- Diagnostic procedures include laboratory tests, endoscopy, radiology, and physiological assessments like anorectal manometry and defecography.
- Therapeutic options encompass lifestyle modifications, pharmacotherapy, biofeedback, and surgical interventions.
Main Results:
- A comprehensive history and physical exam are crucial for identifying alarm symptoms and secondary causes, particularly drug-induced constipation.
- Lifestyle modifications are the first line of treatment.
- Pharmacological options include bulk/osmotic laxatives, lubiprostone, and linaclotide, used sequentially based on treatment response.
Conclusions:
- The management of constipation hinges on a stepwise diagnostic and therapeutic approach.
- Non-operative management, including lifestyle changes and pharmacotherapy, is the mainstay of treatment.
- Surgical intervention is reserved for refractory cases with confirmed delayed intestinal transit.
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