Related Experiment Video
Updated: Nov 6, 2025

11:52
Microbubble Fabrication of Concave-porosity PDMS Beads
Published on: December 15, 2015
8.5K
Fabrication of a Novel Protein Sponge with Dual-Scale Porosity and Mixed Wettability Using a Clean and Versatile
Judith Wemmer1, Loredana Malafronte1, Socrates Foschini1
1Laboratory of Food Process Engineering, Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 9, 8092 Zurich, Switzerland.
Materials (Basel, Switzerland)
|May 5, 2021
Summary
Researchers developed a novel protein sponge from whey proteins using a clean, scalable drying method. This unique material exhibits mixed wettability and dual-scale porosity, enabling efficient absorption of various liquids for diverse industrial applications.
Area of Science:
- Materials Science
- Biotechnology
- Food Science
Background:
- Protein-based materials offer biocompatibility and biodegradability.
- Developing scalable and additive-free fabrication methods for protein structures is crucial for industrial adoption.
- Whey proteins are abundant, renewable biomaterials with potential for advanced applications.
Purpose of the Study:
- To fabricate an open-porous protein sponge with mixed wettability entirely from whey proteins.
- To investigate the effects of microwave-convection drying on foam structure and protein denaturation.
- To explore the potential applications of the developed protein sponge in biomedicine, pharmaceuticals, and the food industry.
Main Methods:
- Additive-free foaming of whey protein solutions.
- Controlled microwave-convection drying to induce volumetric heating and foam stabilization.
- Characterization of the resulting porous structure, including dual-scale porosity and mixed wettability.
- Assessment of liquid absorption properties for polar and non-polar liquids.
Main Results:
- A stable, open-porous protein sponge was successfully fabricated using whey proteins.
- The microwave-convection drying process promoted foam expansion, prevented collapse, and induced protein denaturation.
- The resulting sponge exhibited dual-scale porosity with interconnected macroscopic and microscopic pores.
- The protein sponge demonstrated rapid absorption of both polar (water) and non-polar liquids due to its mixed wettability and capillary system.
Conclusions:
- The developed protein sponge offers a promising biomaterial for various applications.
- The fabrication method is clean, scalable, and avoids additives.
- The material's unique properties, including mixed wettability and dual-porosity, allow for versatile liquid handling and potential use in separation, delivery, or absorption systems.

