Preventive Intervention Program on the Outcomes of Very Preterm Infants and Caregivers: A Multicenter Randomized

Young-Ah Youn1, Seung-Han Shin2, Ee-Kyung Kim2

  • 1Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

Brain Sciences
|May 5, 2021
PubMed

Insights

A specialized nurse home visit and group session program did not significantly improve neurodevelopmental outcomes for very preterm infants. This intervention showed no impact on cognitive, motor, or language development at 10 and 24 months corrected age.

Area of Science:

  • Neonatal Medicine
  • Developmental Pediatrics
  • Public Health

Background:

  • Very preterm infants face increased risks of neurodevelopmental and behavioral disabilities.
  • Early identification and intervention are crucial for improving outcomes in this vulnerable population.

Purpose of the Study:

  • To evaluate the effectiveness of a preventive intervention program involving home visits and group sessions for very preterm infants and their parents.
  • To assess the impact on neurodevelopmental outcomes, maternal depression, and mother-child attachment.

Main Methods:

  • A multicenter randomized controlled trial involving 138 preterm infants (gestational age ≤30 weeks or birth weight ≤1500 g).
  • Infants were randomized to an intervention group (specialized nurse home visits and group sessions) or a control group.
  • Neurodevelopmental outcomes were assessed using Bayley-III scores at 10 and 24 months corrected age.

Main Results:

  • No significant differences were observed between the intervention and control groups in cognitive, motor, or language domains of Bayley-III scores at 10 and 24 months corrected age.
  • Maternal depression, mother-child attachment, and infant social-emotional assessment scores also showed no significant differences between groups.

Conclusions:

  • The tested preventive intervention program, including home visits and group sessions, did not demonstrate significant benefits for the neurodevelopmental outcomes of very preterm infants.
  • Further research may be needed to explore alternative or modified interventions to support this population.

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