Related Experiment Video
Updated: Nov 6, 2025
Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
Published on: March 13, 2018
A one-pot fluorogenic cascade cyclization reaction via BF3-sensing
Moumi Mandal1, Ajit Kumar Mahapatra1, Arik Kar1
1Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711 103, India. akar@chem.iiests.ac.in akmahapatra@chem.iiests.ac.in.
Abstract:
(E)-3-Phenyl-1-(2-(phenylethynyl) phenyl) prop-2-en-1-one is shown as a chemodosimetric sensor where it selectively senses toxic BF3, scrutinized through electronic spectral analysis and recognized with the naked eye. The probable binding mechanism is proposed based on the electronic spectral analysis, NMR titration and the ESI-MS technique. The incredible increase in fluorescence intensity (60-fold) in less than 2 minutes along with an extremely low detection limit (6.36 × 10-10 M) in a range of 0-50 μl make it function as a proficient gas phase BF3 sensor with synchronized detection in a portable form.
