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Updated: Nov 6, 2025

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

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Myocardial Strain Imaging in Resistant Hypertension

Reem Alsharari1,2,3, David Oxborough2, Gregory Y H Lip2,4

  • 1Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.

Current Hypertension Reports
|May 5, 2021
PubMed

Insights

Resistant hypertension (RH) can cause significant cardiac changes. Two-dimensional speckle tracking echocardiography (STE) shows promise in assessing cardiac remodeling and early dysfunction in patients with uncontrolled hypertension.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Hypertension Research

Background:

  • Resistant hypertension (RH) is a significant risk factor for cardiovascular diseases and mortality.
  • Chronic high blood pressure leads to cardiac remodeling, including impaired left ventricular (LV) function, left ventricular hypertrophy (LVH), myocardial fibrosis, and left atrial (LA) enlargement.

Purpose of the Study:

  • To review the utility of two-dimensional speckle tracking echocardiography (STE) for assessing cardiac remodeling in hypertensive patients, particularly those with uncontrolled RH.
  • To highlight the potential benefits of STE as a non-invasive imaging technique in this population.

Main Methods:

  • Review of recent literature on echocardiography and resistant hypertension.
  • Focus on the application of two-dimensional speckle tracking echocardiography (STE) in evaluating cardiac changes.

Main Results:

  • Conventional echocardiography is useful for assessing hypertension-mediated organ damage (HMOD).
  • STE offers advanced risk assessment and can detect early-stage LV dysfunction and myocardial fibrosis, outperforming conventional 2D parameters.

Conclusions:

  • STE is a promising echocardiographic marker for evaluating cardiac remodeling and dysfunction in patients with hypertension and RH.
  • STE provides valuable insights beyond conventional echocardiography for risk stratification.
Abstract

Keywords:
Deformation imagingHigh blood pressureResistant hypertensionSpeckle trackingSystolic dysfunctionUncontrolled hypertension

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