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Updated: Nov 6, 2025

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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
Published on: November 2, 2019
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Secondary lymphedema from cancer therapy
Michael Bernas1, Saskia R J Thiadens2, Paula Stewart3
1TCU and UNTHSC School of Medicine, Fort Worth, TX, USA. m.bernas@tcu.edu.
Clinical & Experimental Metastasis
|May 5, 2021
Summary
This review summarizes secondary lymphedema after cancer treatment. It covers diagnosis, imaging, genetics, patient education, and treatment options for this common side effect.
Area of Science:
- Oncology
- Medical Rehabilitation
Background:
- Secondary lymphedema is a common sequela of cancer treatment.
- Understanding its incidence, diagnosis, and management is crucial for patient care.
Purpose of the Study:
- To provide a comprehensive overview of secondary lymphedema following cancer therapy.
- To highlight current knowledge and identify gaps in the field.
Main Methods:
- Review of findings presented at the 8th International Congress on Cancer Metastasis.
- Inclusion of patient and therapist perspectives alongside medical professionals.
- Exploration of diagnostic, imaging, genetic, and treatment modalities.
Main Results:
- Lymphedema definition, diagnosis, and incidence are explored.
- Imaging techniques and genetic research are discussed.
- Patient education, early detection, conservative, and surgical treatments are examined.
Conclusions:
- The manuscript offers valuable updates on secondary lymphedema.
- It addresses incidence, diagnosis, early detection, and rehabilitation for cancer survivors.
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