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Axial length targets for myopia control.

Paul Chamberlain1, Percy Lazon de la Jara1, Baskar Arumugam1

  • 1CooperVision Inc., Pleasanton, USA.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|May 5, 2021
PubMed
Summary
This summary is machine-generated.

Myopia control contact lenses slowed eye elongation in children to levels similar to normal eye growth in emmetropes. This suggests physiological eye growth may limit myopia control effectiveness.

Keywords:
axial lengthchildrencontact lensesmyopiamyopia control

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Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Myopia Research

Background:

  • Eye elongation occurs in both emmetropic and myopic children.
  • Understanding normal eye growth is crucial for evaluating myopia control interventions.

Purpose of the Study:

  • Compare axial elongation in untreated myopes, treated myopes, and emmetropes.
  • Contextualize myopia progression within normal emmetropic eye growth.
  • Assess potential limits of myopia control based on physiological eye growth.

Main Methods:

  • Utilized data from a 3-year myopia control contact lens trial (MiSight® 1 day).
  • Compared trial data with axial elongation data from the Orinda Longitudinal Study of Myopia (OLSM) and Singapore Cohort Study of the Risk Factors for Myopia (SCORM).
  • Calculated annual axial elongation using published study equations and created virtual cohorts for comparison.

Main Results:

  • Untreated myopes showed 3-year axial elongation (0.62 mm) comparable to OLSM (0.70 mm) and SCORM (0.65 mm) models.
  • Emmetropic virtual cohorts exhibited 3-year elongation of 0.24 mm (OLSM/SCORM), similar to MiSight-treated myopes (0.30 mm).

Conclusions:

  • Myopia control treatments brought axial elongation closer to that of emmetropes.
  • Hypothesize that myopic elongation is superimposed on physiological emmetropic eye growth.
  • Suggest myopia control may minimize pathological elongation while preserving physiological growth.