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Updated: Jan 20, 2026

Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs
Published on: March 3, 2023
Preliminary Report From the Pelvic Floor Disorders Consortium: Large-Scale Data Collection Through Quality
Paul M Cavallaro1, Sarah A Vogler2, Neil H Hyman3
1Pelvic Floor Disorders Center, Section of Colon and Rectal Surgery, Massachusetts General Hospital, Boston, Massachusetts.
Surgical repair of rectal prolapse improved function in all patients. Quality improvement initiatives can systematically collect data, but larger cohorts are needed to compare surgical procedure effectiveness. A robust database is recommended.
Area of Science:
- Colorectal Surgery
- Pelvic Floor Disorders
- Surgical Quality Improvement
Background:
- Rectal prolapse management is evolving, but clinical trials lack conclusive evidence on operative approaches.
- Numerous studies have not yielded definitive conclusions on the best surgical techniques.
Purpose of the Study:
- To report preliminary data from a large-scale quality improvement initiative focused on functional outcomes in rectal prolapse repair.
- To measure and improve functional results for patients undergoing rectal prolapse surgery.
Main Methods:
- Retrospective analysis of prospectively collected surgical quality improvement data.
- Inclusion of 181 consecutive patients undergoing external rectal prolapse repair across 14 tertiary centers (2017-2019).
- Preoperative and 3-month postoperative assessment using Wexner incontinence and Altomare obstructed defecation scores.
Main Results:
- Abdominal surgery (n=112) included suture rectopexy and ventral rectopexy; perineal approaches (n=68) were used in older patients with more comorbidities.
- Both abdominal and perineal repairs showed similar functional improvements (Wexner, Altomare scores).
- Ventral mesh rectopexy demonstrated a greater reduction in pad usage compared to posterior suture rectopexy.
Conclusions:
- All patients experienced functional improvements after rectal prolapse surgery.
- Larger patient cohorts are required to establish the superiority of specific surgical procedures.
- Quality improvement methods offer a practical approach to data acquisition and analysis for pelvic floor disorders.
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Related Concept Videos
05:47Isolation and Characterization of the Murine Uterosacral Ligaments and Pelvic Floor Organs
07:41Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse
03:49Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System
Data Reporting and Recording
Data Collection II
Data Collection I