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Revision of the ARRIVE guidelines: rationale and scope
Nathalie Percie du Sert1, Viki Hurst1, Amrita Ahluwalia2
1NC3Rs, London, UK.
BMJ Open Science
|May 6, 2021
Summary
The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines aim to improve animal research reporting. A revised strategy will enhance guideline implementation and reporting quality in scientific publications.
Area of Science:
- Life Sciences
- Biomedical Research
- Animal Welfare
Background:
- The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were introduced in 2010 to enhance the reporting standards of animal research.
- Despite widespread endorsement, the ARRIVE guidelines have had a limited impact on improving the quality of reporting in animal research publications.
Purpose of the Study:
- To outline the strategy of an expert working group tasked with revising the ARRIVE guidelines.
- To facilitate greater uptake and impact of the ARRIVE guidelines within the scientific community.
Main Methods:
- The expert working group's strategy focuses on three key areas for guideline revision and implementation.
- These areas include prioritizing ARRIVE items into a tiered system, creating an explanation and elaboration document, and revising specific guideline items.
Main Results:
- The current impact of the ARRIVE guidelines on reporting quality has been limited.
- A strategic revision and focused implementation plan are underway to address this limitation.
Conclusions:
- The expert working group's revised strategy aims to significantly improve the quality of reporting in animal research.
- Enhanced guideline clarity, prioritization, and support materials are expected to increase ARRIVE guideline adoption and effectiveness.
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