Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Early neuropsychological outcomes following pediatric acquired brain injury: a prospective longitudinal pilot study.

Applied neuropsychology. Child·2026

Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026

Same author

Baseline clinical profile of patients with obstructive hypertrophic cardiomyopathy in the Italian Mavacamten early access program.

International journal of cardiology·2026

Same author

Clinical practice guidelines for the management of non-functioning advanced GEP-NENs: a GRADE approach for evidence evaluation and recommendations by the Italian Association of Medical Oncology (AIOM) in collaboration with the Italian Association for Neuroendocrine Tumors (ITANET).

ESMO open·2025

Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025

Same author

Coastal methane emissions driven by aerotolerant methanogens using seaweed and seagrass metabolites.

Nature geoscience·2025

Search research articles

Related Experiment Video

Updated: Nov 6, 2025

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Published on: April 28, 2022

Anatomic features in SCAD assessed by CCT: A propensity score matching case control study.

C Di Donna¹, A U Cavallo¹, L Pugliese¹

¹Division of Radiology, University Hospital Policlinico "Tor Vergata", Viale Oxford, 81, 00133 Rome, Italy.

Annales De Cardiologie Et D'Angeiologie

|May 7, 2021

Summary

Spontaneous coronary artery dissection (SCAD) is linked to shorter left main artery length and sharper angles at coronary artery branches. These anatomical features may increase shear stress, raising SCAD risk in middle-aged individuals.

Keywords:

Anatomic features Caractéristiques anatomiques Coefficient de propension Coronary arteries computed tomography Coroscanner Dissection spontanée des artères coronaires Dynamique des fluides Fluid dynamics Propensity score matching Spontaneous coronary artery dissection

More Related Videos

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

Related Experiment Videos

Last Updated: Nov 6, 2025

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Published on: April 28, 2022

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

Area of Science:

Cardiology
Medical Imaging
Biomechanical Engineering

Background:

Spontaneous coronary artery dissection (SCAD) can affect individuals without traditional cardiovascular risk factors.
Understanding the anatomical predispositions to SCAD is crucial for risk stratification and prevention.

Purpose of the Study:

To investigate the anatomical features of coronary arteries in patients with SCAD.
To compare these features with those of healthy individuals using coronary arteries computed tomography (CCT).

Main Methods:

Retrospective analysis of CCT scans from 11 SCAD patients and 11 matched healthy controls.
Evaluation of anatomical parameters including left main (LM) length, angles between coronary arteries, ostial distances, and vessel tortuosity.
Fluid dynamic analysis to assess shear stress on vessel walls.

Main Results:

SCAD patients exhibited significantly shorter LM length and a sharper angle between the left anterior descending (LAD) artery and its first branch compared to controls.
A higher tortuosity score was observed in the SCAD group.
Fluid dynamics revealed that angles less than 90 degrees at the first bifurcation, combined with high tortuosity, can increase vessel wall strain.

Conclusions:

Coronary artery tortuosity and specific branching angles may contribute to increased shear stress.
These biomechanical factors are implicated in the pathogenesis of SCAD.