Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasma lipid patterns in patients with suspected glaucoma.

I A Chisholm1, S Stead

  • 1Department of Ophthalmology, University of Saskatchewan, Saskatoon.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|June 1, 1988
PubMed
Summary

Plasma lipid and lipoprotein analysis in suspected glaucoma patients revealed higher hypertriglyceridemia in women. However, lipid profiles were not useful for diagnosing glaucoma or assessing cardiovascular disease risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hospital resource endowments and nosocomial infections: longitudinal evidence from the English National Health Service on Clostridioides difficile between 2011 and 2019.

The Journal of hospital infection·2023
Same author

A portable electrochemical magnetoimmunosensor for detection of sulfonamide antimicrobials in honey.

Analytical and bioanalytical chemistry·2013
Same author

Management and diagnosis of glaucoma for the family physician.

Canadian family physician Medecin de famille canadien·2011
Same author

Meeting maximum residue limits: an improved screening technique for the rapid detection of antimicrobial residues in animal food products.

Food additives and contaminants·2004
Same author

Papaverine induces apoptosis in vascular endothelial and smooth muscle cells.

Life sciences·2002
Same author

Detection of streptomycin and dihydrostreptomycin residues in milk, honey and meat samples using an optical biosensor.

The Analyst·2002

Area of Science:

  • Ophthalmology
  • Cardiovascular Science
  • Clinical Biochemistry

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Lipid and lipoprotein abnormalities are associated with cardiovascular disease.
  • The relationship between lipid profiles and glaucoma requires further investigation.

Purpose of the Study:

  • To analyze plasma lipid and lipoprotein levels in patients with suspected glaucoma.
  • To determine if lipid profiles can aid in glaucoma diagnosis or risk stratification.
  • To explore the association between lipid abnormalities and cardiovascular disease in this patient cohort.

Main Methods:

  • Analysis of plasma lipid and lipoprotein levels.
  • Inclusion of 183 patients (92 women, 91 men) with suspected glaucoma.

Related Experiment Videos

  • Categorization of lipoprotein abnormalities, including hypertriglyceridemia and Type IV lipoproteinemia.

    • Main Results:

    • An excess of hypertriglyceridemia was observed in women.
    • Type IV lipoproteinemia was the most frequent lipoprotein abnormality.
    • Lipid analysis did not help determine the presence or type of glaucoma.
    • Cardiovascular disease prevalence was similar in patients with and without lipoprotein abnormalities.

    Conclusions:

    • Plasma lipid and lipoprotein profiles are not effective diagnostic tools for glaucoma.
    • Hypertriglyceridemia is more prevalent in women with suspected glaucoma.
    • Lipid abnormalities in this cohort did not correlate with cardiovascular disease prevalence.