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Three-Dimensional Printing in Cleft Care: A Systematic Review.

Farrukh R Virani1, Evan C Chua2, Mary Roz Timbang1

  • 1Department of Otolaryngology-Head and Neck Surgery, University of California Davis Medical Center, Sacramento, CA, USA.

The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
|May 7, 2021
PubMed
Summary
This summary is machine-generated.

3D printing offers diverse applications in cleft lip and palate care, including surgical planning and device creation. Further research needs standardized reporting on clinical outcomes and costs for this technology.

Keywords:
3-dimensional printinganatomic modelbioprintingcleft lipcleft palatenasoalveolar moldingpatient educationpatient-specific implantssurgical simulationsurgical training

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Area of Science:

  • Biomedical Engineering
  • Craniofacial Surgery
  • Medical Technology

Background:

  • Cleft lip and palate (CLP) treatment requires innovative approaches.
  • 3-Dimensional (3D) printing, also known as additive manufacturing, presents emerging solutions.

Purpose of the Study:

  • To review current applications of 3D printing in CLP patient care.
  • To assess limitations, financial aspects, and future implications of 3D printing in this field.

Main Methods:

  • A retrospective systematic review was conducted.
  • Three independent reviewers screened articles from major databases (Cochrane, Ovid Medline, Embase) using specific search terms.
  • Inclusion criteria focused on English-language studies with original data relevant to 3D printing and CLP.

Main Results:

  • Thirty-nine of 84 identified articles met the criteria.
  • Applications included nasoalveolar molding (11 studies), patient-specific implants (6 studies), surgical planning (8 studies), anatomic models (8 studies), and surgical simulation (6 studies).
  • Bioprinting was explored in 4 studies, and cost analysis in 8 studies.

Conclusions:

  • 3D printing demonstrates significant potential in managing cleft lip and palate.
  • Current literature is primarily descriptive, lacking robust clinical outcome data.
  • Standardized reporting on clinical outcomes, costs, and technical parameters is crucial for future advancements.