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Related Concept Videos

Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

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Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
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Gastritis-I: Introduction and Types01:27

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Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
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Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

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The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Rates and Risk Factors for Interval Gastric Cancers at Screening Gastroscopy.

Jin Hwa Park1, Kang Nyeong Lee1, Hang Lak Lee1

  • 1Department of Internal Medicine, Hanyang University School of Medicine, Seoul, South Korea.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
|May 7, 2021
PubMed
Summary
This summary is machine-generated.

Interval gastric cancers (GCs) are a significant concern during screening gastroscopy. Careful observation, especially in the lower stomach, and longer examination times may help reduce their occurrence.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Medical Diagnostics

Background:

  • Interval gastric cancers (GCs) are diagnosed between regular endoscopic screenings.
  • Understanding the incidence and risk factors for interval GCs is crucial for improving early cancer detection strategies.

Purpose of the Study:

  • To determine the rate of interval gastric cancers detected during screening gastroscopy.
  • To identify clinico-pathological characteristics and risk factors associated with interval GCs.

Main Methods:

  • Retrospective analysis of 54,724 screening gastroscopies performed between 2005 and 2017.
  • Classification of gastric cancers into interval GC and initially diagnosed GC groups based on endoscopic history.
  • Multivariate analysis to evaluate risk factors for interval GCs.

Main Results:

  • 43 interval GCs were identified, representing 18.4% of all diagnosed GCs.
  • Interval GCs were smaller and associated with shorter observation times and location in the low-to-mid-body of the stomach.
  • Factors like differentiation, ulcerated type, metaplasia, H. pylori infection, and endoscopist experience were not significantly associated with interval GCs.

Conclusions:

  • The incidence of interval GCs during screening gastroscopy is notable.
  • Increasing endoscopic observation time, focusing on smaller lesions, and meticulous examination of the low-to-mid-gastric region may help decrease interval GC rates.