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Updated: Nov 6, 2025

In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy
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Published on: September 11, 2013

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Achievement in active agent structures as a power tools in tumor angiogenesis imaging

Katarzyna Staszak1, Karolina Wieszczycka1, Anna Bajek2

  • 1Institute of Technology and Chemical Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznan, Poland.

Biochimica Et Biophysica Acta. Reviews on Cancer
|May 9, 2021
PubMed

Insights

This review explores chemical compounds for imaging and monitoring tumor angiogenesis, a key process in cancer progression. It highlights advancements in techniques like PET, MRI, and SPECT for better cancer detection and management.

Area of Science:

  • Oncology
  • Radiochemistry
  • Medical Imaging

Background:

  • Cancer is a leading global cause of death, with tumor angiogenesis crucial for its growth and spread.
  • Effective monitoring of tumor angiogenesis is vital for cancer treatment strategies.

Purpose of the Study:

  • To review recent developments in chemical compounds used for imaging and monitoring tumor angiogenesis.
  • To provide a comprehensive understanding of the chemistry behind tumor angiogenesis imaging techniques.

Main Methods:

  • Review of current literature on active agents for tumor angiogenesis imaging.
  • Analysis of chemical compounds utilized in Positron Emission Tomography (PET), Magnetic Resonance Imaging (MRI), and Single Photon Emission Computed Tomography (SPECT).
  • Inclusion of hybrid imaging techniques such as PET/MRI and PET/CT.

Main Results:

  • Significant progress has been made in developing chemical agents for visualizing tumor angiogenesis.
  • Various imaging modalities, including PET, MRI, and SPECT, are effectively employed using these agents.
  • Hybrid imaging techniques offer enhanced diagnostic capabilities for tumor angiogenesis.

Conclusions:

  • Chemical compounds play a critical role in the advancement of tumor angiogenesis imaging.
  • Continued research in this area promises improved diagnostic tools for cancer monitoring and treatment.
Keywords:
Contrast agentImagingMRIPETSPECTTracerTumor angiogenesis

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