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Rhinomaxillary mucormycosis presenting as palatal ulcer: A case report with comprehensive pathophysiology
Meenal Verma1, Rakhee Sharma1, Nikhil Verma2
1Department of Oral Pathology, Geetanjali Dental and Research Institute, Udaipur, Rajasthan, India.
Journal of Oral and Maxillofacial Pathology : JOMFP
|May 10, 2021
Summary
Mucormycosis is a dangerous fungal infection, especially in immunocompromised individuals and uncontrolled diabetics. Early diagnosis is challenging, making histopathology crucial for definitive identification and management.
Area of Science:
- Mycology
- Infectious Diseases
- Pathogenesis
Background:
- Mucormycosis presents a significant threat to immunocompromised patients, particularly those with uncontrolled diabetes.
- Accurate diagnosis is often delayed due to non-specific early imaging and unreliable cytological smears.
Observation:
- This case report details a 58-year-old female diagnosed with rhinomaxillary mucormycosis.
- The patient had a history of uncontrolled diabetes mellitus.
Findings:
- Histopathological examination remains the gold standard for definitive diagnosis of mucormycosis.
- Understanding host-fungus interactions is key for effective histopathological evaluation and treatment.
Implications:
- Despite current treatments, mortality rates for mucormycosis remain high in persistently immunocompromised individuals.
- Improved diagnostic strategies and a deeper understanding of pathogenesis are needed to improve patient outcomes.
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